Reliable Aseptic Filling Machines for Four-Barrel Use

Overview

The Aseptic Filling Machine for Four Barrel Use is a high-capacity, precision-engineered solution designed for the aseptic filling of liquids, semi-solids, and viscous products in pharmaceutical, biotech, food, and beverage industries. With a four-barrel configuration, it delivers parallelized filling processes, maximizing efficiency while maintaining strict sterility and compliance with global standards (e.g., cGMP, ISO, ASEP).

Key Features

Four-Barrel Parallel Filling

• High Throughput: Simultaneously fill up to 4 products or lines at once, doubling or quadrupling production capacity compared to single-barrel systems.

• Independent Control: Each barrel operates with its own servo-driven pumps, valves, and weight cells for precise, individualized filling.

Aseptic & Sterility Assurance

• SIP/COP Capability: Steam-in-place (SIP) and clean-out-of-place (COP) functions for automated sterilization of barrels, hoses, and nozzles.

• Isolator Technology: Optional RABS (Restricted Access Barrier Systems) or fully enclosed isolator designs to prevent contamination.

• A-Class Cleanroom Compatibility: Constructed with stainless steel 316L and polished surfaces (Ra < 0.4 μm).

Precision Filling Technology

• Weight-Based Filling: Integrated load cells with ±0.1% accuracy for consistent fill volumes.

• Nozzle Design: Customizable contact/non-contact nozzles for vials, bottles, pouches, or syringes.

• Foam Control: Vacuum or nitrogen purging to minimize product foaming during filling.

Flexibility & Versatility

• Multi-Product Handling: Quick changeover between different products or container types (e.g., glass vials, plastic bottles, bags).

• Fill Volume Range: 1–500 ml per container, adjustable via HMI (Human-Machine Interface).

• Viscosity Handling: Suitable for low-viscosity (water-like) to high-viscosity (syrups, creams) products.

Automation & Integration

• PLC & HMI Controls: Touchscreen interface for recipe storage, real-time monitoring, and remote troubleshooting.

• Robotic Integration: Compatible with pick-and-place robots for automated container loading/unloading.

• Data Logging: Ethernet/IP connectivity for traceability, batch reporting, and compliance with 21 CFR Part 11.

Safety & Compliance

• Locked Seals: Automated clamp closures and pressure sensors to ensure leak-proof operations.

• Particle Detection: Inline laser or vision systems to reject contaminated containers.

• Validation Pack: IQ/OQ/PQ documentation, calibration certificates, and performance protocols included.

Optional Enhancements

• Stopper/Cap Placement: Automated crimping, screw capping, or stopper insertion modules.

• Labeling Systems: Inline printers/applicators for expiration dates, lot numbers, or barcodes.

• Nitrogen Flushing: Overhead or nozzle-based purging to preserve product integrity post-fill.

• Weight Checking: Inline checkweighers for 100% weight verification.

Applications

• Pharmaceuticals: Sterile injectables, ophthalmic solutions, vaccines, and oral liquids.

• Biotech: Cell cultures, protein solutions, and gene therapy vectors.

• Food & Beverage: Juices, dairy products, sauces, and ready-to-eat meals in aseptic pouches.

• Chemicals: Specialty chemicals requiring aseptic handling (e.g., cosmetics, industrial fluids).

Technical Specifications

• Filling Speed: Up to 1,200 containers/hour (per barrel) depending on product and container type.

• Fill Accuracy: ±0.2–0.5% (adjustable via HMI).

• Materials: Stainless steel 316L, silicone gaskets, and certified cleanroom polymers.

• Power: 220V/380V/480V (customizable), 10–20 kW.

• Footprint: Compact design (e.g., 3m x 2m x 2.5m) with modular expansion options.

• Environment: Designed for Class A–D cleanrooms or ISO 5–8 environments.

Benefits

1. Productivity: Four-barrel design reduces cycle time and increases output without compromising sterility.

2. Flexibility: Supports multi-product runs and container formats with quick changeovers.

3. Compliance: Full traceability, validation packages, and cGMP-compliant design.

4. Low Risk: SIP/COP sterilization and isolator options minimize cross-contamination.

5. ROI: High throughput and reduced labor costs lead to rapid return on investment.

Why Choose This Machine?

Engineered for speed, precision, and sterility, this four-barrel aseptic filler combines parallel processing with advanced automation to meet the demands of high-volume production while ensuring patient safety and product integrity. Perfect for manufacturers requiring scalable, reliable, and compliant aseptic filling solutions.

Ready to optimize your aseptic filling line? Contact us for a customized quote and workflow analysis!

Immediate Order:

Website: http://www.wwbiotec.com/product/drumfillingmachines-en.html

Alibaba: https://www.alibaba.com/product-detail/High-Speed-Drum-Filling-Machine-Automatic_1601405682760.html?spm=a2747.product_manager.0.0.515e2c3cjNCu3K

China Manufacturing Co Ltd.: https://fillingmachinecn.en.made-in-china.com